4-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluorophenylamino)-N-(2,4-difluorophenyl)nicotinamide → 4-(4-(3-(2,4-Difluorophenylcarbamoyl)pyridin-4-ylamino)-2-fluorophenoxy)picolinamide
Reaction equation
[NH2:1][c:2]1[cH:3][c:4]([F:18])[c:5]([O:6][c:7]2[cH:8][c:9]([C:13](=[O:14])[NH2:15])[n:10][cH:11][cH:12]2)[cH:16][cH:17]1.[nH:19]1[c:20]2[n:21][cH:22][cH:23][c:24]([O:25][c:26]3[cH:27][cH:28][c:29]([NH:30][c:36]4[cH:37][cH:38][n:39][cH:40][c:41]4[C:42](=[O:43])[NH:44][c:45]4[c:46]([F:52])[cH:47][c:48]([F:51])[cH:49][cH:50]4)[cH:31][c:32]3[F:33])[c:34]2[cH:35][cH:53]1>>[NH:1]([c:2]1[cH:3][c:4]([F:18])[c:5]([O:6][c:7]2[cH:8][c:9]([C:13](=[O:14])[NH2:15])[n:10][cH:11][cH:12]2)[cH:16][cH:17]1)[c:36]1[cH:37][cH:38][n:39][cH:40][c:41]1[C:42](=[O:43])[NH:44][c:45]1[c:46]([F:52])[cH:47][c:48]([F:51])[cH:49][cH:50]1Participants
3
Sources & evidence
- ORD record
- ord-1a227843fadd42c693d7082156912987
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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