2-Bromo-1,3,4-trifluorobenzene → [6-Methoxy-2-(2,3,6-trifluoro-phenyl)-naphthalen-1-yl]-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-methanone

HRID 287765Notes

Reaction equation

HRID 287765 reaction equation
[Br:38][c:39]1[c:40]([F:47])[cH:41][cH:42][c:43]([F:46])[c:44]1[F:45].[CH3:1][O:2][c:3]1[cH:4][c:5]2[cH:6][cH:7][c:8]([O:30][S:31]([C:32]([F:33])([F:34])[F:35])(=[O:36])=[O:37])[c:9]([C:13]([c:14]3[cH:15][cH:16][c:17]([O:20][CH2:21][CH2:22][N:23]4[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]4)[cH:18][cH:19]3)=[O:29])[c:10]2[cH:11][cH:12]1>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[cH:6][cH:7][c:8](-[c:39]3[c:40]([F:47])[cH:41][cH:42][c:43]([F:46])[c:44]3[F:45])[c:9]([C:13]([c:14]3[cH:15][cH:16][c:17]([O:20][CH2:21][CH2:22][N:23]4[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]4)[cH:18][cH:19]3)=[O:29])[c:10]2[cH:11][cH:12]1

Participants

3

Reactant 2

HCID 27364012-Bromo-1,3,4-trifluorobenzeneHCID 11685250Trifluoromethanesulfonic acid 6-methoxy-1-[4-(2-piperidin-1-yl-ethoxy)benzoyl]-naphthalen-2-yl ester

Product 1

HCID 57552525[6-Methoxy-2-(2,3,6-trifluoro-phenyl)-naphthalen-1-yl]-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-methanone

Sources & evidence

ORD record
ord-80077244040c40f7bc801d02332b5f25
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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