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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 288051Generated: October 26, 2026

1-(Chloromethyl)-2-(trifluoromethyl)benzene → 1'-[2-(trifluoromethyl)benzyl]-2,3-dihydrospiro[furo[2,3-g][1,4]benzodioxine-8,3'-indol]-2'(1'H)-one

https://huagongshe.com/reaction/288051

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Chloromethyl)-2-(trifluoromethyl)benzeneHCID 89028—
Reactant2-(Bromomethyl)tetrahydro-2H-pyranHCID 141917—
ReactantSpiro[furo[2,3-g]-1,4-benzodioxin-8(7H),3'-[3H]indol]-2'(1'H)-one, 2,3-dihydroHCID 58224164—
Product1'-[2-(trifluoromethyl)benzyl]-2,3-dihydrospiro[furo[2,3-g][1,4]benzodioxine-8,3'-indol]-2'(1'H)-oneHCID 59352319—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-ab91ec43c1b04b86bb31b60d8ab3c985
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)