HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Trifluoromethyl)benzylamine → 3-chlorophenyl-2-(1-hydroxycyclohexyl)-N-[4-(trifluoromethyl)benzyl]acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Trifluoromethyl)benzylamine | HCID 76804 | — |
| Reactant | (3-Chlorophenyl)(1-hydroxycyclohexyl)acetic acid | HCID 68853928 | — |
| Product | 3-chlorophenyl-2-(1-hydroxycyclohexyl)-N-[4-(trifluoromethyl)benzyl]acetamide | HCID 68853662 | — |
Reaction Steps
In an analogous manner to Example 1, step 1 2-(3-chlorophenyl-2-(1-hydroxycyclohexyl)-N-[4-(trifluoromethyl)benzyl]acetamide was prepared from (3-chlorophenyl)(1-hydroxycyclohexyl)acetic acid (Reference Example 1-a) and 4-trifluoromethylbenzylamine. MS (ESI) m/z 426/428 ([M+H]+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07419980B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-8d3110dfd2bf4e63817e96aa0027f33d |
| Source note | uspto-grants-2008_09 |