HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-[(3S)-3-(methylamino)piperidin-1-yl]-1-[3-(trifluoromethoxy)phenyl]ethyl}cyclohexanol dihydrochloride → HCID 86600411, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-[(3S)-3-(methylamino)piperidin-1-yl]-1-[3-(trifluoromethoxy)phenyl]ethyl}cyclohexanol dihydrochloride | HCID 11155707 | — |
| Reactant | HCID 86600413 | HCID 86600413 | — |
| Product | HCID 86600411 | HCID 86600411 | — |
Reaction Steps
In an analogous manner to Example 13, step 2, 1-(2-[(3S)-3-(methylamino)piperidin-1-yl]-1-[3-(trifluoromethoxy)phenyl]ethyl}cyclohexanol dihydrochloride was prepared from tert-butyl ((3S)-1-{(1-hydroxycyclohexyl)[3-(trifluoromethoxy)phenyl]acetyl}piperidin-3-yl)carbamate. MS m/z 401; HRMS: calcd for C21H31F3N2O2+H, 401.24159; found (ESI, [M+H]+), 401.2419.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07419980B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-8f79359485e2423e9320706a4526c89b |
| Source note | uspto-grants-2008_09 |