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HRID28824

反应详情

EQUATION

反应方程式

HRID 28824 的结构方程式

REACTANTS

反应物

2
结构：Cl.Cl.N[C@H]1CCN(CC(c2cccc(OC(F)(F)F)c2)C2(O)CCCCC2)C1
HCID68851317

未命名化合物

结构：CC(C)(C)OC(=O)N[C@H]1CCN(C(=O)C(c2cccc(OC(F)(F)F)c2)C2(O)CCCCC2)C1
HCID86600416

未命名化合物

PRODUCTS

生成物

1
结构：CC(c1cccc(OC(F)(F)F)c1)C1(O)CCCCC1N1CC[C@H](N)C1.Cl.Cl
HCID86600414

未命名化合物

PROCEDURE

实验过程

In an analogous manner to Example 1, step 2, 1-{2-[(3S)-3-aminopyrrolidin-1-yl]-1-[3-(trifluoromethoxy)phenyl]ethyl}cyclohexanol dihydrochloride was prepared from tert-butyl ((3S)-1-{(1-hydroxycyclohexyl)[3-(trifluoromethoxy)phenyl]acetyl}pyrrolidin-3-yl)carbamate MS (ESI) m/z 373; HRMS: calcd for C19H27F3N2O2+H, 373.21029; found (ESI, [M+H]+), 373.2106.