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HRID28826

反应详情

EQUATION

反应方程式

HRID 28826 的结构方程式

REACTANTS

反应物

2
结构：CN(C)[C@H]1CCN(CC(c2cccc(C(F)(F)F)c2)C2(O)CCCCC2)C1.Cl.Cl
HCID68852618

未命名化合物

结构：Cl.Cl.N[C@H]1CCN(CC(c2cccc(C(F)(F)F)c2)C2(O)CCCCC2)C1
HCID68855271

未命名化合物

PRODUCTS

生成物

1
结构：CC(c1cccc(C(F)(F)F)c1)C1(O)CCCCC1N1CC[C@H](N(C)C)C1.Cl.Cl
HCID86600417

未命名化合物

PROCEDURE

实验过程

In an analogous manner to Example 36, 1-{2-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]-1-[3-(trifluoromethyl)phenyl]ethyl}cyclohexanol dihydrochloride was prepared from, 1-{2-[(3S)-3-aminopyrrolidin-1-yl]-1-[3-(trifluoromethyl)phenyl]ethyl}cyclohexanol (See Example 221). MS (ES) m/z 385.1; HRMS: calcd for C21H31F3N2O+H, 385.24667; found (ESI, [M+H]+), 385.2454.