反应详情

3.34 g of lithium aluminum hydride are placed in a 250-cm3 flask, and ether is added gently with stirring. Using a dropping funnel, 5 g of methyl (7-methoxy-1-naphthyl)acetate previously dissolved in 50 cm3 of ether are added slowly. The reaction medium is left stirring for 30 minutes. It is poured very slowly into a mixture of water and ice so as to hydrolyze the excess unreacted hydride. The reaction medium is filtered. The aqueous phase is extracted with 3 times 50 cm3 of ether, and the ether phases are dried over magnesium sulfate and evaporated. The white solid obtained is recrystallized.

1. additionare added slowly
2. waitThe reaction medium is left
3. stirringstirring for 30 minutes
4. filtrationThe reaction medium is filtered
5. extractionThe aqueous phase is extracted with 3 times 50 cm3 of ether
6. dry with materialthe ether phases are dried over magnesium sulfate
7. customevaporated
8. customThe white solid obtained
9. customis recrystallized