5-Fluoromethoxypyridine-2-carboxylic acid → N-[3-(2-amino-5,5-difluoro-4,6,6-trimethyl-1,3-oxazin-4-yl)-4-fluorophenyl]-5-(fluoromethoxy)pyridine-2-carboxamide
Reaction equation
[F:21][CH2:22][O:23][c:24]1[cH:25][cH:26][c:27]([C:30](=[O:31])[OH:32])[n:28][cH:29]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]([F:20])[c:6]([C:8]2([CH3:19])[N:9]=[C:10]([NH2:18])[O:11][C:12]([CH3:16])([CH3:17])[C:13]2([F:14])[F:15])[cH:7]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([F:20])[c:6]([C:8]2([CH3:19])[N:9]=[C:10]([NH2:18])[O:11][C:12]([CH3:16])([CH3:17])[C:13]2([F:14])[F:15])[cH:7]1)[C:30]([c:27]1[cH:26][cH:25][c:24]([O:23][CH2:22][F:21])[cH:29][n:28]1)=[O:31]Participants
3
Sources & evidence
- ORD record
- ord-6a6f0c50dad2465bb13ba251b7b9888d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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