HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[1-{4-[(4-Bromo-2-fluorobenzyl)oxy]-3-chlorophenyl}-2-(4-methylpiperazin-1-yl)ethyl]cyclohexanol → HCID 68853905, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[1-{4-[(4-Bromo-2-fluorobenzyl)oxy]-3-chlorophenyl}-2-(4-methylpiperazin-1-yl)ethyl]cyclohexanol | HCID 59701220 | — |
| Reactant | 1-[1-(3-chloro-4-{[2-(trifluoromethyl)benzyl]oxy}phenyl)-2-piperazin-1-ylethyl]cyclohexanol Dihydrochloride | HCID 86599408 | — |
| Product | HCID 68853905 | HCID 68853905 | — |
Reaction Steps
In an analogous manner to Example 24, 1-{1-[4-[(4-bromo-2-fluorobenzyl)oxy}-3-chlorophenyl]-2-(4-methylpiperazin-1-yl)ethyl]cyclohexanol was prepared from 1-(1-{4-[(4-bromo-2-fluorobenzyl)oxy]-3-chlorophenyl}-2-piperazin-1-ylethyl)cyclohexanol dihydrochloride (See Example 421). MS (ESI) m/z 539; HRMS: calcd for C26H33BrClFN2O2+H+, 539.14707; found (ESI, [M+H]+), 539.1453.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07419980B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-e71a6973932e4c2fac748b361b5e7b26 |
| Source note | uspto-grants-2008_09 |