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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 28858Generated: October 30, 2026

Ethyl isocyanate → N-ethyl-N'-{4-[1-ethyl-4-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl]phenyl}urea

https://huagongshe.com/reaction/28858

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl isocyanateHCID 8022—
Reactant4-[1-ethyl-4-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl]anilineHCID 69002692—
ProductN-ethyl-N'-{4-[1-ethyl-4-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl]phenyl}ureaHCID 58980007—

Reaction Steps

Following the procedure described in Example 1 using 4-[1-ethyl-4-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl]aniline and ethyl isocyanate afforded the title compound. ESMS [M+H]+: 393.4

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07419988B2
Source datasetuspto-grants-2008_09
ORD IDord-325ef6aec2c141adb9933c81dd5081b8
Source noteuspto-grants-2008_09