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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 288651Generated: October 30, 2026

Hydrochloric Acid → 2-chloro-N-[1-[5-[4-methyl-5-(trifluoromethyl)-1,2-oxazol-3-yl]thiophene-2-carbonyl]piperidin-3-yl]acetamide

https://huagongshe.com/reaction/288651

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantChloroacetyl chlorideHCID 6577—
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
Reactant(3-Aminopiperidin-1-yl)-[5-[4-methyl-5-(trifluoromethyl)-1,2-oxazol-3-yl]thiophen-2-yl]methanoneHCID 68905315—
Product2-chloro-N-[1-[5-[4-methyl-5-(trifluoromethyl)-1,2-oxazol-3-yl]thiophene-2-carbonyl]piperidin-3-yl]acetamideHCID 68909383—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-f752761fe2cb4d8f8fa50c217870b916
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)