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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 28874Generated: October 25, 2026

2-Thiopheneacetyl chloride → n-{4-[1-Ethyl-4-(1h-pyrrolo[2,3-b]pyridin-4-yl)-1h-pyrazol-3-yl]phenyl}-2-(2-thienyl)acetamide

https://huagongshe.com/reaction/28874

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Thiopheneacetyl chlorideHCID 162362—
Reactant4-[1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl]anilineHCID 68999813—
Productn-{4-[1-Ethyl-4-(1h-pyrrolo[2,3-b]pyridin-4-yl)-1h-pyrazol-3-yl]phenyl}-2-(2-thienyl)acetamideHCID 58980032—

Reaction Steps

Following the procedure described in Example 1 with 4-[1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl]aniline and thiophene-2-acetyl chloride provided the title compound. ESMS [M+H]+: 428.4

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07419988B2
Source datasetuspto-grants-2008_09
ORD IDord-6b2a7364bdf5482083d670413a78fdcc
Source noteuspto-grants-2008_09