Methanol → Carvedilol

HRID 288753Notes

Reaction equation

HRID 288753 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]([CH2:9][CH:10]([CH2:11][O:12][c:13]1[cH:14][cH:15][cH:16][c:17]2[nH:18][c:19]3[cH:20][cH:21][cH:22][cH:23][c:24]3[c:25]12)[OH:26])[CH2:27][CH2:28][O:29][c:30]1[c:31]([O:36][CH3:37])[cH:32][cH:33][cH:34][cH:35]1.[CH3:38][OH:39]>>[NH:8]([CH2:9][CH:10]([CH2:11][O:12][c:13]1[cH:14][cH:15][cH:16][c:17]2[nH:18][c:19]3[cH:20][cH:21][cH:22][cH:23][c:24]3[c:25]12)[OH:26])[CH2:27][CH2:28][O:29][c:30]1[c:31]([O:36][CH3:37])[cH:32][cH:33][cH:34][cH:35]1

Participants

3

Reactant 2

HCID 887MethanolHCID 110383641-{benzyl[2-(2-methoxyphenoxy)ethyl]amino}-3-(9H-carbazol-4-yloxy)propan-2-ol

Product 1

HCID 2585Carvedilol

Sources & evidence

ORD record
ord-61d5830e4f9049f293da2863e4b8d23c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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