Ethyl isocyanate → HCID 46888772, compound

HRID 28887Notes

Reaction equation

HRID 28887 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:12]([C:13]3[CH:18]=[CH:17][N:16]=[C:15]4[NH:19][C:20]([C:22]5[CH:27]=[CH:26][CH:25]=[C:24]([CH2:28][N:29]6[CH2:34][CH2:33][O:32][CH2:31][CH2:30]6)[CH:23]=5)=[CH:21][C:14]=34)=[CH:11][N:10]([CH2:35][CH3:36])[N:9]=2)=[CH:4][CH:3]=1.[CH2:37]([N:39]=[C:40]=[O:41])[CH3:38]>>[CH3:38][CH2:37][NH:39][C:40]([NH:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[C:12]([C:13]3[CH:18]=[CH:17][N:16]=[C:15]4[C:14]=3[CH:21]=[C:20]([C:22]3[CH:27]=[CH:26][CH:25]=[C:24]([CH2:28][N:29]5[CH2:30][CH2:31][O:32][CH2:33][CH2:34]5)[CH:23]=3)[NH:19]4)=[CH:11][N:10]([CH2:35][CH3:36])[N:9]=2)=[CH:6][CH:7]=1)=[O:41]

Participants

3

Reactant 2

HCID 8022Ethyl isocyanateHCID 689992304-[3-(4-Aminophenyl)-1-ethyl-1h-pyrazol-4-yl]-2-[3-(n-morpholinylmethyl)phenyl]-1h-pyrrolo[2,3-b]pyridine

Product 1

HCID 46888772HCID 46888772, compound

Procedure

Following the procedure described in Example 48 using 4-[3-(4-aminophenyl)-1-ethyl-1H-pyrazol-4-yl]-2-[3-(N-morpholinylmethyl)phenyl]-1H-pyrrolo[2,3-b]pyridine and ethyl isocyanate provided the title compound. ESMS (M+H)+: 550.6

Sources & evidence

ORD record
ord-dcaee469eb4445dc931ca2b08f7aa063
Source dataset
uspto-grants-2008_09
Patent number
US07419988B2

Reaction notes

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