HCID 58980031, compound → HCID 58980067, compound

HRID 28896Notes

Reaction equation

HRID 28896 reaction equation
C([N:4]1[CH2:13][CH2:12][C:11]2[C:6](=[CH:7][C:8]([C:14]3[NH:41][C:17]4=[N:18][CH:19]=[CH:20][C:21]([C:22]5[C:23]([C:29]6[CH:34]=[CH:33][C:32]([NH:35][C:36](=[O:40])[N:37]([CH3:39])[CH3:38])=[CH:31][CH:30]=6)=[N:24][N:25]([CH2:27][CH3:28])[CH:26]=5)=[C:16]4[CH:15]=3)=[CH:9][CH:10]=2)[CH2:5]1)(=O)C>C(O)C>[CH2:27]([N:25]1[CH:26]=[C:22]([C:21]2[CH:20]=[CH:19][N:18]=[C:17]3[NH:41][C:14]([C:8]4[CH:7]=[C:6]5[C:11]([CH2:12][CH2:13][NH:4][CH2:5]5)=[CH:10][CH:9]=4)=[CH:15][C:16]=23)[C:23]([C:29]2[CH:34]=[CH:33][C:32]([NH:35][C:36](=[O:40])[N:37]([CH3:39])[CH3:38])=[CH:31][CH:30]=2)=[N:24]1)[CH3:28]

Participants

3

Reactant 1

HCID 58980031HCID 58980031, compound

Product 1

HCID 58980067HCID 58980067, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Following the procedure described in Example 11 using N′-(4-{4-[2-(2-acetyl-1,2,3,4-tetrahydro-7-isoquinolinyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-1-ethyl-1H-pyrazol-3-yl}phenyl)-N,N-dimethylurea in ethanol at 100° C. provided the title compound. ESMS [M+H]+: 507.4

Sources & evidence

ORD record
ord-0d2120ccaa754189a2c19197a37df264
Source dataset
uspto-grants-2008_09
Patent number
US07419988B2

Reaction notes

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