2-(Ethylamino)ethanol → HCID 24816133, compound

HRID 28898Notes

Reaction equation

HRID 28898 reaction equation
[CH:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]2[NH:35][C:12]3=[N:13][CH:14]=[CH:15][C:16]([C:17]4[C:18]([C:23]5[CH:28]=[CH:27][C:26]([NH:29][C:30](=[O:34])[N:31]([CH3:33])[CH3:32])=[CH:25][CH:24]=5)=[N:19][N:20]([CH3:22])[CH:21]=4)=[C:11]3[CH:10]=2)=[CH:5][CH:4]=1)=O.[CH2:36]([NH:38][CH2:39][CH2:40][OH:41])[CH3:37]>>[CH2:36]([N:38]([CH2:1][C:3]1[CH:4]=[CH:5][C:6]([C:9]2[NH:35][C:12]3=[N:13][CH:14]=[CH:15][C:16]([C:17]4[C:18]([C:23]5[CH:28]=[CH:27][C:26]([NH:29][C:30](=[O:34])[N:31]([CH3:33])[CH3:32])=[CH:25][CH:24]=5)=[N:19][N:20]([CH3:22])[CH:21]=4)=[C:11]3[CH:10]=2)=[CH:7][CH:8]=1)[CH2:39][CH2:40][OH:41])[CH3:37]

Participants

3

Reactant 2

HCID 80722-(Ethylamino)ethanolHCID 86613318HCID 86613318, compound

Product 1

HCID 24816133HCID 24816133, compound

Procedure

Following the procedure described for Intermediate 101 using N′-(4-{4-[2-(4-formylphenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-1-methyl-1H-pyrazol-3-yl}phenyl)-N,N-dimethylurea and 2-(ethylamino)ethanol provided the title compound. ESMS [M+H]+: 538.4

Sources & evidence

ORD record
ord-36f636093de14b408113c895fadc877e
Source dataset
uspto-grants-2008_09
Patent number
US07419988B2

Reaction notes

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