Pyridine → phenyl(tetrahydro-4H-pyran-4-ylidene)acetonitrile

HRID 289131Notes

Reaction equation

HRID 289131 reaction equation
[OH:1][C:2]1([CH:8]([C:9]#[N:10])[c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[CH2:3][CH2:4][O:5][CH2:6][CH2:7]1.[S:17]([Cl:18])([Cl:19])=[O:20].[cH:21]1[cH:22][cH:23][n:24][cH:25][cH:26]1>>[C:2]1(=[C:8]([C:9]#[N:10])[c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[CH2:3][CH2:4][O:5][CH2:6][CH2:7]1

Participants

4

Reactant 3

HCID 1049PyridineHCID 24386Thionyl ChlorideHCID 58415919(4-hydroxytetrahydro-2H-pyran-4-yl)(phenyl)acetonitrile

Product 1

HCID 58415944phenyl(tetrahydro-4H-pyran-4-ylidene)acetonitrile

Sources & evidence

ORD record
ord-9914b55ab8c542fab61cea8678a1fdc5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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