HRID28924

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCn1cc(B2OC(C)(C)C(C)(C)O2)c(-c2ccc([N+](=O)[O-])cc2)n1

HCID68995348

未命名化合物

结构：O=C([O-])N1CC=C(c2cc3c(Br)ccnc3n2S(=O)(=O)c2ccccc2)CC1

HCID86613320

未命名化合物

PRODUCTS

生成物

结构：CCn1cc(-c2ccnc3c2cc(C2=CCN(C(=O)OC(C)(C)C)CC2)n3S(=O)(=O)c2ccccc2)c(-c2ccc([N+](=O)[O-])cc2)n1

HCID68998400

未命名化合物

PROCEDURE

实验过程

Following the procedure described for Intermediate 11 with 4-[4-bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-3,6-dihydro-1(2H)-pyridinecarboxylate and 1-ethyl-3-(4-nitrophenyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole gave the title compound. ESMS [M+H]+: 655.4

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-56cb8c9bd6f64904a613993d4926ddc3
来源数据集: uspto-grants-2008_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07419988B2
来源说明: uspto-grants-2008_09

反应 SMILES

Br[C:2]1[CH:7]=[CH:6][N:5]=[C:4]2[N:8]([S:20]([C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)(=[O:22])=[O:21])[C:9]([C:11]3[CH2:12][CH2:13][N:14]([C:17]([O-:19])=[O:18])[CH2:15][CH:16]=3)=[CH:10][C:3]=12.[CH2:29]([N:31]1[CH:35]=[C:34](B2OC(C)(C)C(C)(C)O2)[C:33]([C:45]2[CH:50]=[CH:49][C:48]([N+:51]([O-:53])=[O:52])=[CH:47][CH:46]=2)=[N:32]1)[CH3:30]>>[CH2:29]([N:31]1[CH:35]=[C:34]([C:2]2[CH:7]=[CH:6][N:5]=[C:4]3[N:8]([S:20]([C:23]4[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=4)(=[O:22])=[O:21])[C:9]([C:11]4[CH2:12][CH2:13][N:14]([C:17]([O:19][C:3]([CH3:10])([CH3:4])[CH3:2])=[O:18])[CH2:15][CH:16]=4)=[CH:10][C:3]=23)[C:33]([C:45]2[CH:46]=[CH:47][C:48]([N+:51]([O-:53])=[O:52])=[CH:49][CH:50]=2)=[N:32]1)[CH3:30]