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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 28928Generated: October 26, 2026

4-Bromo-1H-pyrrolo[2,3-b]pyridine → 4-[1-{[4-(methyloxy)phenyl]methyl}-3-(4-nitrophenyl)-1H-pyrazol-4-yl]-1H-pyrrolo[2,3-b]pyridine

https://huagongshe.com/reaction/28928

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-1H-pyrrolo[2,3-b]pyridineHCID 22273643—
Reactant1-{[4-(methyloxy)phenyl]methyl}-3-(4-nitrophenyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazoleHCID 69000582—
Product4-[1-{[4-(methyloxy)phenyl]methyl}-3-(4-nitrophenyl)-1H-pyrazol-4-yl]-1H-pyrrolo[2,3-b]pyridineHCID 68999259—

Reaction Steps

Following the procedure described for Intermediate 6 with 4-bromo-1H-pyrrolo[2,3-b]pyridine and 1-{[4-(methyloxy)phenyl]methyl}-3-(4-nitrophenyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole provided the title compound. ESMS [M+H]+: 426.2

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07419988B2
Source datasetuspto-grants-2008_09
ORD IDord-25da7620a0204050bed2e48c617c1760
Source noteuspto-grants-2008_09