HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butylhydrazine monohydrochloride → 1-tert-Butyl-5-(4-nitrophenyl)-1H-pyrazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butylhydrazine monohydrochloride | HCID 81889 | — |
| Reactant | 1,1-dimethylethyl [3-(4-nitrophenyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]acetate | HCID 86617390 | — |
| Product | 1-tert-Butyl-5-(4-nitrophenyl)-1H-pyrazole | HCID 53485527 | — |
Reaction Steps
Following the procedure described for Intermediate 1 with t-butylhydrazine hydrochloride, provided the title compound as the major isomer (80%). ESMS (M-C(CH3)3+2H): 190.0; HNMR (400 MHz, d6-DMSO) δ 8.32 (d, 2H), 7.7 (d, 2H), 7.48 (d, 1H), 6.25 (d, 1H), 1.42 (s, 9H)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07419988B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-c1e9681fb1d646448f308a1fe43670f9 |
| Source note | uspto-grants-2008_09 |