Toluene → 4-{6-[8-Cyclopentyl-6-(2-ethoxy-ethoxy)-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidin-2-ylamino]-pyridin-3-yl}-piperazine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:26]([CH3:27])([CH3:28])([CH3:29])[O:30][C:31](=[O:32])[N:33]1[CH2:34][CH2:35][N:36]([c:39]2[cH:40][n:41][c:42]([NH2:45])[cH:43][cH:44]2)[CH2:37][CH2:38]1.[CH3:46][c:47]1[cH:48][cH:49][cH:50][cH:51][cH:52]1.[CH:1]1([n:6]2[c:7](=[O:25])[c:8]([O:19][CH2:20][CH2:21][O:22][CH2:23][CH3:24])[cH:9][c:10]3[c:11]2[n:12][c:13]([S:16]([CH3:17])=[O:18])[n:14][cH:15]3)[CH2:2][CH2:3][CH2:4][CH2:5]1.[Cl:53][CH2:54][Cl:55]>>[CH:1]1([n:6]2[c:7](=[O:25])[c:8]([O:19][CH2:20][CH2:21][O:22][CH2:23][CH3:24])[cH:9][c:10]3[c:11]2[n:12][c:13]([NH:45][c:42]2[n:41][cH:40][c:39]([N:36]4[CH2:35][CH2:34][N:33]([C:31]([O:30][C:26]([CH3:27])([CH3:28])[CH3:29])=[O:32])[CH2:38][CH2:37]4)[cH:44][cH:43]2)[n:14][cH:15]3)[CH2:2][CH2:3][CH2:4][CH2:5]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-9e0fd7db901f4ec892e3d9b3c21592be
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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