HCID 68998468, compound → HCID 86613331, compound

HRID 28993Notes

Reaction equation

HRID 28993 reaction equation
Br[C:2]1[CH:7]=[CH:6][N:5]=[C:4]2[N:8]([S:19]([C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)(=[O:21])=[O:20])[C:9]([C:11]3[CH:18]=[CH:17][C:14]([CH:15]=[O:16])=[CH:13][CH:12]=3)=[CH:10][C:3]=12.Br[C:29]1[C:30]([C:35]2[CH:40]=[CH:39][C:38]([NH:41][C:42]([N:44]3[CH2:48][CH2:47][CH2:46][CH2:45]3)=[O:43])=[CH:37][CH:36]=2)=[N:31][N:32]([CH3:34])[CH:33]=1>>[CH:15]([C:14]1[CH:13]=[CH:12][C:11]([C:9]2[N:8]([S:19]([C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)(=[O:21])=[O:20])[C:4]3=[N:5][CH:6]=[CH:7][C:2]([C:29]4[C:30]([C:35]5[CH:36]=[CH:37][C:38]([NH:41][C:42]([N:44]6[CH2:45][CH2:46][CH2:47][CH2:48]6)=[O:43])=[CH:39][CH:40]=5)=[N:31][N:32]([CH3:34])[CH:33]=4)=[C:3]3[CH:10]=2)=[CH:18][CH:17]=1)=[O:16]

Participants

3

Reactant 2

HCID 68998468HCID 68998468, compoundHCID 73014046Benzaldehyde, 4-[4-bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-

Product 1

HCID 86613331HCID 86613331, compound

Procedure

Following the procedure described for Intermediate 32 using 4-[4-bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]benzaldehyde and then following the procedure described for Intermediate 100 with N-[4-(4-bromo-1-methyl-1H-pyrazol-3-yl)phenyl]-1-pyrrolidinecarboxamide provided the title compound. ESMS [M+H]+: 631.4.

Sources & evidence

ORD record
ord-615034e041bb4e04a9450fb077a468ce
Source dataset
uspto-grants-2008_09
Patent number
US07419988B2

Reaction notes

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