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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 28995Generated: October 29, 2026

2-(Ethylamino)ethanol → 2-[ethyl({4-[4-[1-(1-methylethyl)-3-(4-nitrophenyl)-1H-pyrazol-4-yl]-1-(phenylsulfonyl)-1H-indol-2-yl]phenyl}methyl)amino]ethanol

https://huagongshe.com/reaction/28995

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Ethylamino)ethanolHCID 8072—
Reactant4-[4-[1-(1-methylethyl)-3-(4-nitrophenyl)-1H-pyrazol-4-yl]-1-(phenylsulfonyl)-1H-indol-2-yl]benzaldehydeHCID 86613326—
Product2-[ethyl({4-[4-[1-(1-methylethyl)-3-(4-nitrophenyl)-1H-pyrazol-4-yl]-1-(phenylsulfonyl)-1H-indol-2-yl]phenyl}methyl)amino]ethanolHCID 68998220—

Reaction Steps

Following the procedure described for Intermediate 101 using 4-[4-[1-(1-methylethyl)-3-(4-nitrophenyl)-1H-pyrazol-4-yl]-1-(phenylsulfonyl)-1H-indol-2-yl]benzaldehyde and 2-(ethylamino)ethanol (18.8 mmol) provided the title compound. ESMS [M+H]+: 665.4.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07419988B2
Source datasetuspto-grants-2008_09
ORD IDord-ebffae60bdd54c3fb51c2f0f7eb616ff
Source noteuspto-grants-2008_09