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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 289983Generated: October 29, 2026

Tetrahydrofuran → (+)-5-Methoxycarbonyl-4-methoxymethyl-1,2,3,6-tetrahydro 2-oxo-6-(3,4-difluorophenyl)-1-[(4-nitrophenyloxy)carbonyl]pyrimidine

https://huagongshe.com/reaction/289983

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
Reactant4-Nitrophenyl chloroformateHCID 82129—
ReactantNpc316347HCID 3280088—
Reactant4-(3,4-Difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl esterHCID 10805035—
Product(+)-5-Methoxycarbonyl-4-methoxymethyl-1,2,3,6-tetrahydro 2-oxo-6-(3,4-difluorophenyl)-1-[(4-nitrophenyloxy)carbonyl]pyrimidineHCID 10672264—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-e4607af515414a3fabc4cbee2bf95506
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)