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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 290450Generated: October 26, 2026

Methanol → (+/-)-5-[1-(2,6-Dimethyl-4'-trifluoromethyl-biphenyl-4-yloxy)-ethyl]-thiophene-2-carboxylic acid ethyl ester

https://huagongshe.com/reaction/290450

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantTolueneHCID 1140—
ReactantTriphenylphosphineHCID 11776—
Reactant1,1'-(Azodicarbonyl)dipiperidineHCID 73042—
Reactant2,6-Dimethyl-4'-(trifluoromethyl)-[1,1'-biphenyl]-4-olHCID 56971749—
ReactantEthyl 5-(1-hydroxyethyl)thiophene-2-carboxylateHCID 59355961—
Product(+/-)-5-[1-(2,6-Dimethyl-4'-trifluoromethyl-biphenyl-4-yloxy)-ethyl]-thiophene-2-carboxylic acid ethyl esterHCID 67485105—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-22942c0eba3e48eaa3e7619116fe4875
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)