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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 290559Generated: October 26, 2026

Hydrochloric Acid → Tert-butyl 4-(2-fluoro-3-(trifluoromethyl)benzoyl)piperazine-1-carboxylate

https://huagongshe.com/reaction/290559

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantChloroformHCID 6212—
Reactant1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 15908—
Reactant1-HydroxybenzotriazoleHCID 75771—
Reactanttert-Butyl piperazine-1-carboxylateHCID 143452—
Reactant2-Fluoro-3-(trifluoromethyl)benzoic acidHCID 518002—
ProductTert-butyl 4-(2-fluoro-3-(trifluoromethyl)benzoyl)piperazine-1-carboxylateHCID 57562617—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-241bd34eede8462596e24cd9e805b0d7
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)