4-(4-Methylpiperazin-1-yl)aniline → 8-Cyclopentyl-2-[4-(4-methyl-piperazin-1-yl)-phenylamino]-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester

HRID 291089Notes

Reaction equation

HRID 291089 reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[c:7](=[O:25])[c:8]2[c:9]([n:10][c:11]([S:14]([CH3:15])(=[O:16])=[O:17])[n:12][cH:13]2)[n:18]([CH:20]2[CH2:21][CH2:22][CH2:23][CH2:24]2)[cH:19]1.[CH3:26][N:27]1[CH2:28][CH2:29][N:30]([c:33]2[cH:34][cH:35][c:36]([NH2:39])[cH:37][cH:38]2)[CH2:31][CH2:32]1>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[c:7](=[O:25])[c:8]2[c:9]([n:10][c:11]([NH:39][c:36]3[cH:35][cH:34][c:33]([N:30]4[CH2:29][CH2:28][N:27]([CH3:26])[CH2:32][CH2:31]4)[cH:38][cH:37]3)[n:12][cH:13]2)[n:18]([CH:20]2[CH2:21][CH2:22][CH2:23][CH2:24]2)[cH:19]1

Participants

3

Reactant 2

HCID 7372534-(4-Methylpiperazin-1-yl)anilineHCID 686792108-Cyclopentyl-2-methanesulfonyl-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester

Product 1

HCID 160594758-Cyclopentyl-2-[4-(4-methyl-piperazin-1-yl)-phenylamino]-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester

Sources & evidence

ORD record
ord-ef5f3839cd5c44e6971e79056956a9be
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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