1-[3-(Trifluoromethyl)pyridin-2-yl]piperazine → 4-Chloro-6-trifluoromethyl-2-[4-(3-trifluoromethylpyridin-2-yl)piperazin-1-yl]-1H-benzoimidazole
Reaction equation
[Cl:1][c:2]1[n:3][c:4]2[c:5]([nH:6]1)[cH:7][c:8]([C:12]([F:13])([F:14])[F:15])[cH:9][c:10]2[Cl:11].[F:16][C:17]([c:18]1[c:19]([N:24]2[CH2:25][CH2:26][NH:27][CH2:28][CH2:29]2)[n:20][cH:21][cH:22][cH:23]1)([F:30])[F:31]>>[c:2]1([N:27]2[CH2:26][CH2:25][N:24]([c:19]3[c:18]([C:17]([F:16])([F:30])[F:31])[cH:23][cH:22][cH:21][n:20]3)[CH2:29][CH2:28]2)[n:3][c:4]2[c:5]([nH:6]1)[cH:7][c:8]([C:12]([F:13])([F:14])[F:15])[cH:9][c:10]2[Cl:11]Participants
3
Sources & evidence
- ORD record
- ord-8de44dccfc5143589f44e6d5a3c24f71
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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