Methanol → Ondelopran

HRID 291311Notes

Reaction equation

HRID 291311 reaction equation
[BH4-:29].[CH3:31][OH:32].[F:1][c:2]1[c:3]([O:4][c:5]2[n:6][cH:7][c:8]([C:9](=[O:10])[NH2:11])[cH:12][cH:13]2)[cH:14][cH:15][c:16]([CH:18]=[O:19])[cH:17]1.[Na+:30].[O:20]1[CH2:21][CH2:22][CH:23]([CH2:26][CH2:27][NH2:28])[CH2:24][CH2:25]1>>[F:1][c:2]1[c:3]([O:4][c:5]2[n:6][cH:7][c:8]([C:9](=[O:10])[NH2:11])[cH:12][cH:13]2)[cH:14][cH:15][c:16]([CH2:18][NH:28][CH2:27][CH2:26][CH:23]2[CH2:22][CH2:21][O:20][CH2:25][CH2:24]2)[cH:17]1

Participants

6

Reactant 5

HCID 887MethanolHCID 923Sodium ionHCID 28123BorohydrideHCID 27731982-(Oxan-4-yl)ethan-1-amineHCID 59730086HCID 59730086, compound

Product 1

HCID 10457387Ondelopran

Sources & evidence

ORD record
ord-a892f87337dd4dc3a015cdd875ca253d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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