Methanol → 2-[4-(3-Fluorophenyl)-4-[2-[3-(2-methylbenzimidazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl]ethyl]piperidin-1-yl]propanoic acid

HRID 291329Notes

Reaction equation

HRID 291329 reaction equation
[CH3:48][OH:49].[F:1][c:2]1[cH:3][c:4]([C:8]2([CH2:26][CH2:27][N:28]3[CH:29]4[CH2:30][CH:31]([n:36]5[c:37]([CH3:45])[n:38][c:39]6[c:40]5[cH:41][cH:42][cH:43][cH:44]6)[CH2:32][CH:33]3[CH2:34][CH2:35]4)[CH2:9][CH2:10][N:11]([CH:14]([C:15](=[O:16])[O:17][CH2:18][c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[CH3:25])[CH2:12][CH2:13]2)[cH:5][cH:6][cH:7]1.[H:46][H:47]>>[F:1][c:2]1[cH:3][c:4]([C:8]2([CH2:26][CH2:27][N:28]3[CH:29]4[CH2:30][CH:31]([n:36]5[c:37]([CH3:45])[n:38][c:39]6[c:40]5[cH:41][cH:42][cH:43][cH:44]6)[CH2:32][CH:33]3[CH2:34][CH2:35]4)[CH2:9][CH2:10][N:11]([CH:14]([C:15](=[O:16])[OH:17])[CH3:25])[CH2:12][CH2:13]2)[cH:5][cH:6][cH:7]1

Participants

4

Reactant 3

HCID 887MethanolHCID 178418361HCID 178418361, compoundHCID 178432113HCID 178432113, compound

Product 1

HCID 724037912-[4-(3-Fluorophenyl)-4-[2-[3-(2-methylbenzimidazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl]ethyl]piperidin-1-yl]propanoic acid

Sources & evidence

ORD record
ord-196426a830d14b1e96428ed3292552f9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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