(4-Fluoro-2-methoxyphenyl)boronic acid → 4-amino-8-(4-fluoro-2-methoxy-phenyl)-N-propyl-cinnoline-3-carboxamide
Reaction equation
[F:19][c:20]1[cH:21][c:22]([O:29][CH3:30])[c:23]([B:26]([OH:27])[OH:28])[cH:24][cH:25]1.[NH2:1][c:2]1[c:3]([C:13](=[O:14])[NH:15][CH2:16][CH2:17][CH3:18])[n:4][n:5][c:6]2[c:7]([Br:12])[cH:8][cH:9][cH:10][c:11]12>>[NH2:1][c:2]1[c:3]([C:13](=[O:14])[NH:15][CH2:16][CH2:17][CH3:18])[n:4][n:5][c:6]2[c:7](-[c:23]3[c:22]([O:29][CH3:30])[cH:21][c:20]([F:19])[cH:25][cH:24]3)[cH:8][cH:9][cH:10][c:11]12Participants
3
Sources & evidence
- ORD record
- ord-785a4939060348aca84496811c01c7cf
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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