4-(3-Amino-2-hydroxypropoxy)-1,3-dihydrobenzimidazol-2-one → 5-[[4-[4-[[2-Hydroxy-3-[(2-oxo-1,3-dihydrobenzimidazol-4-yl)oxy]propyl]amino]piperidin-1-yl]sulfonylphenyl]methyl]-1,3-thiazolidine-2,4-dione

HRID 291530Notes

Reaction equation

HRID 291530 reaction equation
[O:1]=[C:2]1[CH2:3][CH2:4][N:5]([S:8](=[O:9])(=[O:10])[c:11]2[cH:12][cH:13][c:14]([CH2:15][CH:16]3[C:17](=[O:22])[NH:18][C:19](=[O:21])[S:20]3)[cH:23][cH:24]2)[CH2:6][CH2:7]1.[OH:25][CH:26]([CH2:27][O:28][c:29]1[cH:30][cH:31][cH:32][c:33]2[nH:34][c:35](=[O:38])[nH:36][c:37]12)[CH2:39][NH2:40]>>[CH:2]1([NH:40][CH2:39][CH:26]([OH:25])[CH2:27][O:28][c:29]2[cH:30][cH:31][cH:32][c:33]3[nH:34][c:35](=[O:38])[nH:36][c:37]23)[CH2:3][CH2:4][N:5]([S:8](=[O:9])(=[O:10])[c:11]2[cH:12][cH:13][c:14]([CH2:15][CH:16]3[C:17](=[O:22])[NH:18][C:19](=[O:21])[S:20]3)[cH:23][cH:24]2)[CH2:6][CH2:7]1

Participants

3

Reactant 2

HCID 158962374-(3-Amino-2-hydroxypropoxy)-1,3-dihydrobenzimidazol-2-oneHCID 187677925-[4-(4-Oxo-piperidine-1-sulfonyl)-benzyl]-thiazolidine-2,4-dione

Product 1

HCID 187677735-[[4-[4-[[2-Hydroxy-3-[(2-oxo-1,3-dihydrobenzimidazol-4-yl)oxy]propyl]amino]piperidin-1-yl]sulfonylphenyl]methyl]-1,3-thiazolidine-2,4-dione

Sources & evidence

ORD record
ord-54a4227d1e984d149efffe845f6559bd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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