6-Isopropyl-2-phenyl-piperidin-3-ylamine → 6-Methoxy-1-methyl-7-[[(2-phenyl-6-propan-2-ylpiperidin-3-yl)amino]methyl]-3,4-dihydro-1,5-naphthyridin-2-one

HRID 291948Notes

Reaction equation

HRID 291948 reaction equation
[CH3:17][O:18][c:19]1[n:20][c:21]2[c:26]([cH:27][c:28]1[CH:29]=[O:30])[N:25]([CH3:31])[C:24](=[O:32])[CH2:23][CH2:22]2.[CH:1]([CH3:2])([CH3:3])[CH:4]1[CH2:5][CH2:6][CH:7]([NH2:16])[CH:8]([c:10]2[cH:11][cH:12][cH:13][cH:14][cH:15]2)[NH:9]1>>[CH:1]([CH3:2])([CH3:3])[CH:4]1[CH2:5][CH2:6][CH:7]([NH:16][CH2:29][c:28]2[c:19]([O:18][CH3:17])[n:20][c:21]3[c:26]([cH:27]2)[N:25]([CH3:31])[C:24](=[O:32])[CH2:23][CH2:22]3)[CH:8]([c:10]2[cH:11][cH:12][cH:13][cH:14][cH:15]2)[NH:9]1

Participants

3

Reactant 2

HCID 219317156-Isopropyl-2-phenyl-piperidin-3-ylamineHCID 219317642-Methoxy-5-methyl-6-oxo-5,6,7,8-tetrahydro-[1,5]naphthyridine-3-carbaldehyde

Product 1

HCID 219317356-Methoxy-1-methyl-7-[[(2-phenyl-6-propan-2-ylpiperidin-3-yl)amino]methyl]-3,4-dihydro-1,5-naphthyridin-2-one

Sources & evidence

ORD record
ord-db0a34a62c1c44a3aa7c1cbb446e6b61
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…