Ethyl 6-Bromopicolinate → 6-{3-Chloro-4-[3,3,3-trifluoro-2-hydroxy-1-methyl-2-(3-methyl-2-oxo-2,3-dihydro-benzooxazol-5-yl)-propyl]-phenyl}-pyridine-2-carboxylic acid ethyl ester
Reaction equation
[CH2:36]([CH3:37])[O:38][C:39](=[O:40])[c:41]1[n:42][c:43]([Br:47])[cH:44][cH:45][cH:46]1.[Cl:1][c:2]1[c:3]([CH:17]([C:18]([C:19]([F:20])([F:21])[F:22])([OH:23])[c:24]2[cH:25][cH:26][c:27]3[c:28]([n:29]([CH3:33])[c:30](=[O:32])[o:31]3)[cH:34]2)[CH3:35])[cH:4][cH:5][c:6]([B:8]2[O:9][C:10]([CH3:11])([CH3:12])[C:13]([CH3:14])([CH3:15])[O:16]2)[cH:7]1>>[Cl:1][c:2]1[c:3]([CH:17]([C:18]([C:19]([F:20])([F:21])[F:22])([OH:23])[c:24]2[cH:25][cH:26][c:27]3[c:28]([n:29]([CH3:33])[c:30](=[O:32])[o:31]3)[cH:34]2)[CH3:35])[cH:4][cH:5][c:6](-[c:43]2[n:42][c:41]([C:39]([O:38][CH2:36][CH3:37])=[O:40])[cH:46][cH:45][cH:44]2)[cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-dd641f26d189435ea7b4f3f46306bacd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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