Sodium ion → N-{4-[4-amino-2-ethoxymethyl-7-(pyridin-3-yl)-1H-imidazo[4,5-c]quinolin-1-ylmethyl]benzyl}methanesulfonamide

HRID 292423Notes

Reaction equation

HRID 292423 reaction equation
[CH3:1][S:2]([Cl:3])(=[O:4])=[O:5].[Cl:45][CH2:46][Cl:47].[NH2:6][CH2:7][c:8]1[cH:9][cH:10][c:11]([CH2:12][n:13]2[c:14]([CH2:33][O:34][CH2:35][CH3:36])[n:15][c:16]3[c:17]([NH2:32])[n:18][c:19]4[cH:20][c:21](-[c:26]5[cH:27][n:28][cH:29][cH:30][cH:31]5)[cH:22][cH:23][c:24]4[c:25]23)[cH:37][cH:38]1.[Na+:39].[Na+:40].[O-:41][C:42](=[O:43])[O-:44]>>[CH3:1][S:2](=[O:4])(=[O:5])[NH:6][CH2:7][c:8]1[cH:9][cH:10][c:11]([CH2:12][n:13]2[c:14]([CH2:33][O:34][CH2:35][CH3:36])[n:15][c:16]3[c:17]([NH2:32])[n:18][c:19]4[cH:20][c:21](-[c:26]5[cH:27][n:28][cH:29][cH:30][cH:31]5)[cH:22][cH:23][c:24]4[c:25]23)[cH:37][cH:38]1

Participants

6

Reactant 5

HCID 923Sodium ion2×HCID 6344DichloromethaneHCID 19660Carbonate IonHCID 31297Methanesulfonyl chlorideHCID 219840501-(4-aminomethylbenzyl)-2-ethoxymethyl-7-(pyridin-3-yl)-1H-imidazo[4,5-c]quinolin-4-amine

Product 1

HCID 21984108N-{4-[4-amino-2-ethoxymethyl-7-(pyridin-3-yl)-1H-imidazo[4,5-c]quinolin-1-ylmethyl]benzyl}methanesulfonamide

Sources & evidence

ORD record
ord-5336774ee5114a7cb05b7e931a15aff8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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