1,4-Dibenzyl-2-(chloromethyl)piperazine → 1'-({6-Chloro-1-[(1,4-dibenzylpiperazin-2-yl)methyl]-1H-indol-3-yl}carbonyl)-5-fluoro-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one
Reaction equation
[CH2:29]([c:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1)[N:36]1[CH:37]([CH2:49][Cl:50])[CH2:38][N:39]([CH2:42][c:43]2[cH:44][cH:45][cH:46][cH:47][cH:48]2)[CH2:40][CH2:41]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([C:11](=[O:12])[N:13]3[CH2:14][CH2:15][C:16]4([O:17][C:18](=[O:26])[c:19]5[c:20]4[cH:21][cH:22][c:23]([F:25])[cH:24]5)[CH2:27][CH2:28]3)[cH:7][nH:8][c:9]2[cH:10]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([C:11](=[O:12])[N:13]3[CH2:14][CH2:15][C:16]4([O:17][C:18](=[O:26])[c:19]5[c:20]4[cH:21][cH:22][c:23]([F:25])[cH:24]5)[CH2:27][CH2:28]3)[cH:7][n:8]([CH2:49][CH:37]3[N:36]([CH2:29][c:30]4[cH:31][cH:32][cH:33][cH:34][cH:35]4)[CH2:41][CH2:40][N:39]([CH2:42][c:43]4[cH:44][cH:45][cH:46][cH:47][cH:48]4)[CH2:38]3)[c:9]2[cH:10]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-2423d6793a3846a9ab886cf48d4a7196
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…