Dichloromethane → 4-[(3,5-Dimethyl-pyridin-2-ylmethyl)-(3-phenyl-pyridin-2-ylmethyl)-amino]-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([NH:14][CH2:15][c:16]2[n:17][cH:18][cH:19][cH:20][c:21]2-[c:22]2[cH:23][cH:24][cH:25][cH:26][cH:27]2)[CH2:12][CH2:13]1.[CH3:28][c:29]1[c:30]([CH:36]=[O:37])[n:31][cH:32][c:33]([CH3:35])[cH:34]1.[Cl:38][CH2:39][Cl:40]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([N:14]([CH2:15][c:16]2[n:17][cH:18][cH:19][cH:20][c:21]2-[c:22]2[cH:23][cH:24][cH:25][cH:26][cH:27]2)[CH2:36][c:30]2[c:29]([CH3:28])[cH:34][c:33]([CH3:35])[cH:32][n:31]2)[CH2:12][CH2:13]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-a65d7edf8a7e48729e67025ada4eda0b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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