1-(Methoxycarbonylmethyl)-2-indolecarboxylic acid → HCID 18936515, compound
Reaction equation
[CH2:1]([N:5]([C:10]1[C:15]([O:16][CH3:17])=[CH:14][C:13]([CH3:18])=[CH:12][C:11]=1[O:19][CH3:20])[C:6]([CH2:8][NH2:9])=[O:7])[CH2:2][CH2:3][CH3:4].[CH3:21][O:22][C:23]([CH2:25][N:26]1[C:34]2[C:29](=[CH:30][CH:31]=[CH:32][CH:33]=2)[CH:28]=[C:27]1[C:35](O)=[O:36])=[O:24]>>[CH2:1]([N:5]([C:10]1[C:15]([O:16][CH3:17])=[CH:14][C:13]([CH3:18])=[CH:12][C:11]=1[O:19][CH3:20])[C:6]([CH2:8][NH:9][C:35]([C:27]1[N:26]([CH2:25][C:23]([O:22][CH3:21])=[O:24])[C:34]2[C:29]([CH:28]=1)=[CH:30][CH:31]=[CH:32][CH:33]=2)=[O:36])=[O:7])[CH2:2][CH2:3][CH3:4]Participants
3
Procedure
This product is prepared according to the process described in EXAMPLE 1 from [butyl(2,6-dimethoxy-4-methylphenyl)carbamoyl]methylamine and 1-(methoxycarbonylmethyl)-2-indolecarboxylic acid; M.p.=139° C.; Yield: 90%.
Workup
- customThis product is prepared
Sources & evidence
- ORD record
- ord-6b5216160b2e4600a21050c273b18922
- Source dataset
- uspto-grants-1998_03
- Patent number
- US05731340
Reaction notes
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