HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-1-(2,5-dichlorophenyl)ethanone → 1-Benzo[1,3]dioxol-4-yl-2-bromo-ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-1-(2,5-dichlorophenyl)ethanone | HCID 2756907 | — |
| Reactant | 1-(1,3-Dioxaindan-4-yl)ethan-1-one | HCID 13731006 | — |
| Product | 1-Benzo[1,3]dioxol-4-yl-2-bromo-ethanone | HCID 21864977 | 48% |
Reaction Steps
This compound was prepared from 1-benzo[1,3]dioxol-4-yl-ethanone (2.15 g, 13.1 mmol) in the manner described for 2-bromo-1-(2,5-dichlorophenyl)ethanone (Example I-2), affording 1.54 g (48%) of 1-benzo[1,3]dioxol-4-yl-2-bromo-ethanone as an off-white solid. 1H-NMR (CD2Cl2) δ; 7.41 (dd, J=8.1 Hz, 1H), 7.05 (dd, J=8.1 Hz, 1H), 6.94 (dd, J=8.8 Hz, 1H), 6.13 (s, 2H), 4.55 (s, 2H). TLC Rf=0.28, 15%, ethyl acetate—hexanes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07420066B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-4f5f64c4119a458a852a4bd2f024f67f |
| Source note | uspto-grants-2008_09 |