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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 292694Generated: October 26, 2026

Hydrochloric Acid → (RS)-[3-(tert-butyl-diphenyl-silanyloxy)-2,6-difluoro-phenyl]-hydroxy-acetic acid ethyl ester

https://huagongshe.com/reaction/292694

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantTolueneHCID 1140—
ReactantHexaneHCID 8058—
Reactant1,2-DimethoxyethaneHCID 8071—
ReactantPentamethyldiethylenetriamineHCID 18196—
ReactantEthyl oxoacetateHCID 70211—
ReactantTert-butyl-(2,4-difluoro-phenoxy)-diphenyl-silaneHCID 21904942—
ReactantButyllithiumHCID 178418339—
Product(RS)-[3-(tert-butyl-diphenyl-silanyloxy)-2,6-difluoro-phenyl]-hydroxy-acetic acid ethyl esterHCID 69290212—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-583dcf4dcbe54cee9514ef7e03fcc893
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)