2-(Bromomethyl)-1,4-difluorobenzene → 1-(2,5-Difluorobenzyl)-7-iodo-3,3-dimethyl-3,4-dihydro-1H-pyrido[2,3-b]pyrazin-2-one
Reaction equation
[F:15][c:16]1[c:17]([CH2:18][Br:19])[cH:20][c:21]([F:24])[cH:22][cH:23]1.[I:1][c:2]1[cH:3][c:4]2[c:5]([n:13][cH:14]1)[NH:6][C:7]([CH3:11])([CH3:12])[C:8](=[O:10])[NH:9]2>>[I:1][c:2]1[cH:3][c:4]2[c:5]([n:13][cH:14]1)[NH:6][C:7]([CH3:11])([CH3:12])[C:8](=[O:10])[N:9]2[CH2:18][c:17]1[c:16]([F:15])[cH:23][cH:22][c:21]([F:24])[cH:20]1Participants
3
Sources & evidence
- ORD record
- ord-c5f7d589ab1d47029a082b6d14140be2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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