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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 293078Generated: October 31, 2026

Tetrahydrofuran → 2-[2-Oxo-3-(tetrahydrofuran-3-yl)-2,3-dihydro-1H-benzimidazol-1-yl]-N-(2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[c]pyridine-6,3'-pyrrolo[2,3-b]pyridin]-3-yl)acetamide

https://huagongshe.com/reaction/293078

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantDiisopropylethylamineHCID 81531—
Reactant(+/-)-(2-oxo-3-tetrahydrofuran-3-yl-2,3-dihydro-1H-benzimidazol-1-yl)acetic acidHCID 18449404—
Reactant(+/-)-3-amino-5,7-dihydrospiro[cyclopenta[c]pyridine-6,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-oneHCID 57974077—
Product2-[2-Oxo-3-(tetrahydrofuran-3-yl)-2,3-dihydro-1H-benzimidazol-1-yl]-N-(2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[c]pyridine-6,3'-pyrrolo[2,3-b]pyridin]-3-yl)acetamideHCID 25143870—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-c13c8b283a494ee29165910e3085b63b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)