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HRID29312

反应详情

EQUATION

反应方程式

HRID 29312 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)c1cc2ccccc2o1
HCID10331

2-Benzofurancarboxylic acid

C9H6O3

结构：CC1(C)OB(c2ccc(N)cc2)OC1(C)C
HCID2734620

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

C12H18BNO2

PRODUCTS

生成物

1
结构：CC1(C)OB(c2ccc(NC(=O)c3cc4ccccc4o3)cc2)OC1(C)C
HCID66996737

未命名化合物

收率 83%

PROCEDURE

实验过程

Amide coupling of benzofuran-2-carboxylic acid with 4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenylamine was done according to Example 20, Step 4 to give benzofuran-2-carboxylic acid [4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-amide in 83% yield. 1H NMR (400 MHz, DMSO-d6) δ ppm 1.3 (s, 12 H) 7.4 (m, 1 H) 7.5 (m, 1 H) 7.7 (d, J=8.3 Hz, 2 H) 7.7 (dd, J=8.5, 0.9 Hz, 1 H) 7.8 (m, 4 H) 10.6 (s, 1 H)