Bromide ion → 4-(4-chlorobenzoyl)-1-[4-(2,5-dihydro-1H-pyrrol-1-ylcarbonyl)benzyl]-7-hydroxy-1,3,4,5-tetrahydrobenzo[e][1,4]-diazepin-2-on

HRID 293134Notes

Reaction equation

HRID 293134 reaction equation
[BH3:41].[Br-:38].[Br-:39].[Br-:40].[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:6](=[O:7])[N:8]2[CH2:9][C:10](=[O:35])[N:11]([CH2:21][c:22]3[cH:23][cH:24][c:25]([C:28](=[O:29])[N:30]4[CH2:31][CH:32]=[CH:33][CH2:34]4)[cH:26][cH:27]3)[c:12]3[c:13]([cH:15][c:16]([O:19][CH3:20])[cH:17][cH:18]3)[CH2:14]2)[cH:36][cH:37]1.[Cl:42][CH2:43][Cl:44]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:6](=[O:7])[N:8]2[CH2:9][C:10](=[O:35])[N:11]([CH2:21][c:22]3[cH:23][cH:24][c:25]([C:28](=[O:29])[N:30]4[CH2:31][CH:32]=[CH:33][CH2:34]4)[cH:26][cH:27]3)[c:12]3[c:13]([cH:15][c:16]([OH:19])[cH:17][cH:18]3)[CH2:14]2)[cH:36][cH:37]1

Participants

5

Reactant 4

HCID 259Bromide ion3×HCID 6331BoraneHCID 6344DichloromethaneHCID 226326524-(4-chlorobenzoyl)-1-[4-(2,5-dihydro-1H-pyrrol-1-ylcarbonyl)benzyl]-7-methoxy-1,3,4,5-tetrahydrobenzo[e][1,4]-diazepin-2-on

Product 1

HCID 226326184-(4-chlorobenzoyl)-1-[4-(2,5-dihydro-1H-pyrrol-1-ylcarbonyl)benzyl]-7-hydroxy-1,3,4,5-tetrahydrobenzo[e][1,4]-diazepin-2-on

Sources & evidence

ORD record
ord-dc0013a85a9e41e0b332e3213d29fbda
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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