1,4-Dioxane → Methyl 3-amino-6-(oxazol-2-yl)-5-(trifluoromethyl)picolinate
Reaction equation
[CH2:17]([Sn:18]([CH2:19][CH2:20][CH2:21][CH3:27])([c:22]1[o:23][cH:24][cH:25][n:26]1)[CH2:28][CH2:29][CH2:30][CH3:31])[CH2:32][CH2:33][CH3:34].[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][c:7]([Br:16])[c:8]([C:12]([F:13])([F:14])[F:15])[cH:9][c:10]1[NH2:11].[O:35]1[CH2:36][CH2:37][O:38][CH2:39][CH2:40]1.[cH:41]1[cH:42][cH:43][c:44]([P:45]([Pd:46]([P:47]([c:48]2[cH:49][cH:50][cH:51][cH:52][cH:53]2)([c:54]2[cH:55][cH:56][cH:57][cH:58][cH:59]2)[c:60]2[cH:61][cH:62][cH:63][cH:64][cH:65]2)([P:66]([c:67]2[cH:68][cH:69][cH:70][cH:71][cH:72]2)([c:73]2[cH:74][cH:75][cH:76][cH:77][cH:78]2)[c:79]2[cH:80][cH:81][cH:82][cH:83][cH:84]2)[P:85]([c:86]2[cH:87][cH:88][cH:89][cH:90][cH:91]2)([c:92]2[cH:93][cH:94][cH:95][cH:96][cH:97]2)[c:98]2[cH:99][cH:100][cH:101][cH:102][cH:103]2)([c:104]2[cH:105][cH:106][cH:107][cH:108][cH:109]2)[c:110]2[cH:111][cH:112][cH:113][cH:114][cH:115]2)[cH:116][cH:117]1>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][c:7](-[c:22]2[o:23][cH:24][cH:25][n:26]2)[c:8]([C:12]([F:13])([F:14])[F:15])[cH:9][c:10]1[NH2:11]Participants
5
Sources & evidence
- ORD record
- ord-c2fc2b5c7440428f9a956fc2a57ab496
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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