Acetic Acid → 5-Chloro-N-(5-chloropyridin-2-yl)-2-{[1-(4,4,4-trifluorobut-2-yl)piperidin-4-yl]methylamino}-benzamide
Reaction equation
[C:34]([BH3-:35])#[N:36].[C:38]([OH:39])(=[O:40])[CH3:41].[CH3:42][OH:43].[Cl:1][c:2]1[cH:3][cH:4][c:5]([NH:18][CH2:19][CH:20]2[CH2:21][CH2:22][NH:23][CH2:24][CH2:25]2)[c:6]([C:7](=[O:8])[NH:9][c:10]2[n:11][cH:12][c:13]([Cl:16])[cH:14][cH:15]2)[cH:17]1.[F:26][C:27]([CH2:28][C:29]([CH3:30])=[O:31])([F:32])[F:33].[Na+:37]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([NH:18][CH2:19][CH:20]2[CH2:21][CH2:22][N:23]([CH:29]([CH2:28][C:27]([F:26])([F:32])[F:33])[CH3:30])[CH2:24][CH2:25]2)[c:6]([C:7](=[O:8])[NH:9][c:10]2[n:11][cH:12][c:13]([Cl:16])[cH:14][cH:15]2)[cH:17]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-09d69100ec24481baeef58ec185a1298
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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