Bicarbonate Ion → 5-Chloromethyl-6-fluoro-benzo[1,3]dioxole

HRID 293558Notes

Reaction equation

HRID 293558 reaction equation
[F:1][c:2]1[c:3]([CH2:11][OH:12])[cH:4][c:5]2[c:6]([cH:10]1)[O:7][CH2:8][O:9]2.[Na+:17].[O-:13][C:14]([OH:15])=[O:16].[S:18]([Cl:19])([Cl:20])=[O:21]>>[F:1][c:2]1[c:3]([CH2:11][Cl:20])[cH:4][c:5]2[c:6]([cH:10]1)[O:7][CH2:8][O:9]2

Participants

5

Reactant 4

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 24386Thionyl ChlorideHCID 591291851,3-Benzodioxole-5-methanol, 6-fluoro-

Product 1

HCID 591292085-Chloromethyl-6-fluoro-benzo[1,3]dioxole

Sources & evidence

ORD record
ord-2be7b1bd29cd45b583cf295b556810fe
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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