HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methyl-4-phenyl-benzofuran-2-carboxylic acid tert-butyl ester → 3-Methyl-4-phenyl-benzofuran-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methyl-4-phenyl-benzofuran-2-carboxylic acid tert-butyl ester | HCID 68712893 | — |
| Solvent | Trifluoroacetic acid methylene chloride | HCID 21863450 | — |
| Product | 3-Methyl-4-phenyl-benzofuran-2-carboxylic acid | HCID 68716342 | — |
Reaction Steps
3-Methyl-4-phenyl-benzofuran-2-carboxylic acid tert-butyl ester was dissolved in 2 mL of TFA/dichloromethane (1:1). The solution was stirred at room temperature for 3 h. The solvents were removed under vacuum and the residue was triturated with ether. Filtration gave 66 mg of 3-methyl-4-phenyl-benzofuran-2-carboxylic acid as white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07420001B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-e1ab8c4507624175b4daebc0b85570af |
| Source note | uspto-grants-2008_09 |