2-(Bromomethyl)tetrahydro-2H-pyran → 6-chloro-1'-(pyridin-2-ylmethyl)-2,3-dihydrospiro[furo[3,2-f][1,4]benzodioxine-9,3'-indol]-2'(1'H)-one
Reaction equation
[Br:1][CH2:2][c:3]1[n:4][cH:5][cH:6][cH:7][cH:8]1.[Br:9][CH2:10][CH:11]1[CH2:12][CH2:13][CH2:14][CH2:15][O:16]1.[Cl:17][c:18]1[c:19]2[c:20]([c:21]3[c:22]([cH:27]1)[O:23][CH2:24][CH2:25][O:26]3)[C:28]1([CH2:29][O:30]2)[C:31](=[O:39])[NH:32][c:33]2[cH:34][cH:35][cH:36][cH:37][c:38]21>>[CH2:2]([c:3]1[n:4][cH:5][cH:6][cH:7][cH:8]1)[N:32]1[C:31](=[O:39])[C:28]2([c:20]3[c:19]([c:18]([Cl:17])[cH:27][c:22]4[c:21]3[O:26][CH2:25][CH2:24][O:23]4)[O:30][CH2:29]2)[c:38]2[c:33]1[cH:34][cH:35][cH:36][cH:37]2Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-7fc71d55d56e4966b7126609010ef4c8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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